Procedure and Benefits of Assisted Reproductive Technology Development

This discussion focuses on the progress made in IVF technology, which encompasses its introduction, process, and benefits. It’s crucial to comprehend that three generations of IVF technology exist, each with varying success levels. It’s essential to clarify misunderstandings about these generations and compare and contrast them to comprehend their differences better. The primary difference between the three generations, namely Conventional In Vitro Fertilization (First Generation), In Vitro Fertilization (IVF) with Intracytoplasmic Sperm Injection (ICSI) (Second Generation), and In Vitro Fertilization (IVF) with Pre-implantation Genetic Diagnosis (PGD) (Third Generation) IVF technology, is their applicability to different populations. It’s incorrect to assume that the latest technology is always superior, which is why it’s crucial to comprehend the unique features of each generation of IVF technology to make an informed decision and increase the chances of success.

In Vitro Fertilization (IVF) with Pre-implantation Genetic Diagnosis (PGD)

The third generation of in vitro fertilization is known as preimplantation genetic diagnosis (PGD), which builds upon the technique of the second generation, focusing on genetic diagnosis prior to implantation. Once the embryo reaches the 4- to 8-cell stage, one or two cells (blastomeres) are extracted, and molecular diagnostics are used to conduct genetic testing to ensure the embryo is free from hereditary diseases before implantation.

This technology is suitable for both male and female infertility issues. It is especially appropriate for women over the age of 34 who are in their late maternal age, couples who share a genetic condition, patients with a history of frequent spontaneous abortions, and those with chromosomal abnormalities. By using preimplantation genetic diagnosis and next-generation sequencing (PGS/NGS), this method helps prevent the transmission of genetic diseases from one generation to the next (PGD).

Oocyte Rejuvenation (also known as Pronuclear Transfer or PNT)

The AI embryo selection system is an improved embryo grading system based on the 3.5-generation IVF. The accuracy of this technology depends significantly on the database used during the process, in addition to utilizing the built-in database provided by the Time-lapse manufacturer. With 6 years of experience in reproductive medicine and more successful IVF procedures completed, IVF Asia Group can provide more effective programs for intended patients in the Philippines.